Air Pollution appear to Foster Diabetes

http://bigfigure.blogspot.com/
A pair of new studies one in the United States, another in Germany reports strong proof that diabetes rates climb with increasing air pollution in the form of of tiny airborne particles. “Although previous studies had hinted at this possibility, the data were frequently from small studies or from animals showing to high levels of particulate matter,” notes Aruni Bhatnagar, a cardiovascular researcher at the University of Louisville in Kentucky who did not take part in either study. He says the new data provide important and additional rigorous evidence that real-world pollution may be tampering with blood sugar control in a large and growing number of people.

Both new studies focused on tiny airborne motes spewed mainly by traffic, coal-fired power plants and industrial boilers. The new findings are particularly troubling when set against “an exploding pandemic, if you will, of type 2 diabetes, mostly in urbanized areas around the world,” adds cardiologist Sanjay Rajagopalan of the Ohio State University College of Medicine in Columbus, who is also unaffiliated with either latest study. “The traditional explanation for this pandemic,” he says, “has been alter in lifestyle diet and exercise and increasing obesity.”

Particulate pollution is emerging as another potentially main candidate for causing obesity, he says, owing to its skill to trigger chronic, low-grade inflammation initially in the lung but also in a host of other tissues, including fat. Last year, Rajagopalan’s team published data from mice that for the first time established that fine particulate pollution can conspire with obesity to promote metabolic disease. The researchers bare animals for half a year to what’s known as PM-2.5, airborne particulate matter 2.5 micrometers in diameter or smaller. All the animals ate a huge fat diet and became obese.

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