The findings, published on Thursday in the journal Science, oppose the notion that infected adults are behind outbreak in California and elsewhere of whooping cough, an infectious disease caused by the bacterium Bordetella pertussis. A U.S. advisory panel last month suggested that adults over 65 be given a booster of the "Tdap" vaccine for tetanus, diphtheria and pertussis, or whooping cough, to keep infants under a year old, who are too young to be vaccinated. But elder people may not be the major culprit, Pejman Rohani of the University of Michigan and colleagues say.
Whooping cough, which causes unmanageable, violent coughing, infects 30-50 million people a year globally and kills about 300,000, mostly children in rising countries. There are regular outbreaks in developed countries, including one in California that has exaggerated more than 6,400 people and killed at least 10 infants, the U.S. Centers for Disease Control and Prevention said. To study the belongings of social connections on distribution whooping cough, the research team used a situation in Sweden. That country halt its whooping cough vaccination program in 1979 because of vaccine security concerns, and did not resume routine vaccination for 17 years. But health establishment continued to track cases of whooping cough by age group.
"We took advantage of an unexpected natural experiment," Rohani said in a telephone interview. The group compare this to a 2008 study of more than 7,000 people from eight European country that tracked social contacts by age. They plugged this into a computer model to see how social associates affected the extend of whooping cough. The team found that when Sweden resumes vaccinating young children, there was a big drop in the number of cases of whooping cough in all age categories excepting in teenagers. With the model of social mixing, children frequently interact with other children, and are unlikely to be infected by adults, they found.
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Whooping cough, which causes unmanageable, violent coughing, infects 30-50 million people a year globally and kills about 300,000, mostly children in rising countries. There are regular outbreaks in developed countries, including one in California that has exaggerated more than 6,400 people and killed at least 10 infants, the U.S. Centers for Disease Control and Prevention said. To study the belongings of social connections on distribution whooping cough, the research team used a situation in Sweden. That country halt its whooping cough vaccination program in 1979 because of vaccine security concerns, and did not resume routine vaccination for 17 years. But health establishment continued to track cases of whooping cough by age group.
"We took advantage of an unexpected natural experiment," Rohani said in a telephone interview. The group compare this to a 2008 study of more than 7,000 people from eight European country that tracked social contacts by age. They plugged this into a computer model to see how social associates affected the extend of whooping cough. The team found that when Sweden resumes vaccinating young children, there was a big drop in the number of cases of whooping cough in all age categories excepting in teenagers. With the model of social mixing, children frequently interact with other children, and are unlikely to be infected by adults, they found.
useful links : transport rankings
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