Lung Cancer in Smokers, Nonsmokers May Be a affect Different Disease

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New researches suggest that lung cancer in people who have never smoked may be a dissimilar disease than it is in smokers. Scientists compare the genetic characteristics of lung cancer tumors in 30 people who not at all smoked to tumors in 53 smokers or former smokers. The tumors of people who had not at all smoked had twice as many DNA abnormalities as people who were present or former smokers, said study author Kelsie Thu, a doctoral applicant at the British Columbia Cancer Research Centre in Vancouver. "This is telling there might be incredible different going on with tumors in never smokers," Thu said.

"If we find out lung cancer in never smokers is a different disease and we can recognize what those differences are, maybe we can design specific therapies that goal the genetic alterations in never-smokers and improve the prognosis." The study was to be obtainable Monday at the American Association of Cancer Research's annual meeting, in Philadelphia. Lung cancer is the foremost cause of cancer death in the America for men and woman, according to the American Cancer Society. Lung cancer will kill a predictable 157,000 Americans this year. But it's not now smokers who get it lung cancer is the seventh foremost cause of cancer deaths among people who have not at all smoked, Thu said.

Dana Reeve, wife of the late Christopher Reeve, died in 2006 at age 44 from lung cancer. She had not at all smoked. Prior research has oblique that lung cancer tumors in never-smokers are different than the tumors in smokers. Compare to former and present smokers with lung cancer, never-smokers with lung cancer lean to be diagnosed younger, are more likely to be women and are extra likely to have adenocarcinomas, the majority common type of cancer. Every one of the lung cancer patients in the study had adenocarcinoma. People who never smoked are also more likely to have a change in the epidermal growth issue receptor (EGFR) gene.

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