Cholesterol has long been in scientists' sights, mostly when it comes to the link between high levels and heart disease. Now, researchers are looking at substance produced when the body breaks down cholesterol. Known as oxysterols, these molecules may give to illnesses as varied as Alzheimer's disease and osteoporosis. Eventually, the liver turns oxysterols into bile acids and catch rid of them. But some people have nonstandard levels of oxysterols. Abnormal levels of certain oxysterols have been found in the blood of patients with cardiovascular diseases and several sclerosis.
Some oxysterols are supposed to be toxic to brain neurons and give to decline in Alzheimer's disease. They have also been linked to age connected macular degeneration. Scientists say that someone's level of oxysterols is autonomous of cholesterol levels; someone with high cholesterol can have usual oxysterol levels and someone with usual cholesterol may have abnormal oxysterol levels. There is still a long way to go before scientists fully appreciate the role of oxysterols and whether they directly give to disease. Researchers say the body possibly makes hundreds of types of oxysterols but only a dozen have been personally studied.
Oxysterols are found in the blood and in tissues but only in very little amounts. Measuring them accurately need advanced instruments that are not routinely used in all labs. Moreover, while oxysterols at unusual levels may be toxic, they appear to have optimistic roles too. In the brain, researchers say they help excite cells to send cholesterol to help repair neurons that obtain damaged after injury or disease. They also turn down enzymes that create cholesterol, which helps lower blood cholesterol levels. Scientists say they hope to expand an "oxysterol profile" that would be associated with a certain disease and permit doctors to identify people who might be at high risk for a condition.
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Some oxysterols are supposed to be toxic to brain neurons and give to decline in Alzheimer's disease. They have also been linked to age connected macular degeneration. Scientists say that someone's level of oxysterols is autonomous of cholesterol levels; someone with high cholesterol can have usual oxysterol levels and someone with usual cholesterol may have abnormal oxysterol levels. There is still a long way to go before scientists fully appreciate the role of oxysterols and whether they directly give to disease. Researchers say the body possibly makes hundreds of types of oxysterols but only a dozen have been personally studied.
Oxysterols are found in the blood and in tissues but only in very little amounts. Measuring them accurately need advanced instruments that are not routinely used in all labs. Moreover, while oxysterols at unusual levels may be toxic, they appear to have optimistic roles too. In the brain, researchers say they help excite cells to send cholesterol to help repair neurons that obtain damaged after injury or disease. They also turn down enzymes that create cholesterol, which helps lower blood cholesterol levels. Scientists say they hope to expand an "oxysterol profile" that would be associated with a certain disease and permit doctors to identify people who might be at high risk for a condition.
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lowcost cialis journal,
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