
A new study has revealed that people with obstructive sleep apnea (OSA), a sleep disorder linked with obesity, have more non calcified or "bad" plaque in their coronary arteries. "Our study reveals that persons with disruptive sleep apnea are prone to developing an aggressive form of atherosclerosis that put them at risk for impaired blood flow and cardiovascular actions," said U. Joseph Schoepf, director of cardiovascular imaging at the Medical University of South Carolina in Charleston, S.C.
OSA is reason by obstruction of the upper airway during sleep and is characterize by periodic pauses in breathing, which last for 10 or more seconds. OSA is also usually associated with snoring. In the study, 49 obese patients, mean age 61, with OSA and a mean body mass index of 33, and 46 obese patients without the disorder undergo coronary CT angiography (cCTA), which give detailed pictures and information on plaque buildup and narrowing in the vessels. The OSA group included 26 men and 23 women, and the coordinated control collection included 22 men and 24 women.
The imaging exposed that the amount of calcified plaque in the coronary artery was not significantly different between the two groups, but the overall composition of vessel plaque was particularly different. "Compared to the non OSA group, the patients with OSA had a considerably higher prevalence of non-calcified and mixed plaque," Schoepf said. Non calcified plaque is measured bad plaque, because it is more vulnerable to rupturing and causing a blood clot, which could guide to a heart attack or other cardiovascular event. The study was presented today at the annual gathering of the Radiological Society of North America (RSNA).
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OSA is reason by obstruction of the upper airway during sleep and is characterize by periodic pauses in breathing, which last for 10 or more seconds. OSA is also usually associated with snoring. In the study, 49 obese patients, mean age 61, with OSA and a mean body mass index of 33, and 46 obese patients without the disorder undergo coronary CT angiography (cCTA), which give detailed pictures and information on plaque buildup and narrowing in the vessels. The OSA group included 26 men and 23 women, and the coordinated control collection included 22 men and 24 women.
The imaging exposed that the amount of calcified plaque in the coronary artery was not significantly different between the two groups, but the overall composition of vessel plaque was particularly different. "Compared to the non OSA group, the patients with OSA had a considerably higher prevalence of non-calcified and mixed plaque," Schoepf said. Non calcified plaque is measured bad plaque, because it is more vulnerable to rupturing and causing a blood clot, which could guide to a heart attack or other cardiovascular event. The study was presented today at the annual gathering of the Radiological Society of North America (RSNA).
useful links : transport rankings
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