Dengue patients suffer from capillary permeability, when fluid escape from their blood vessels into surrounding tissues, causing breathing complexity and complications in major organs like the brain, liver and kidneys. "The virus has a crash on the wall of the capillaries and allow more fluids to go away the tubes and into the tissues," said Jeremy Farrar, tropical medicine professor and director of the Oxford University Clinical Research Unit in Vietnam. "The complication is lots of fluids in the lungs which create breathing difficult.
In people who have a high BMI (body mass index), their capillaries are essentially more likely to leak, so that is made worse in a dengue infection," Farrar told Reuters after addressing a communicable disease conference in Singapore. Dengue used to be a disease mainly among young children, but almost anyone is now vulnerable and infection numbers have shot up because of urbanization and the steady movement of people circumstances that allow the Aedes aegypti mosquito, which carries the virus, to thrive.
The World Health Organization estimate there is 50 million dengue infection worldwide each year. Among these are 500,000 harsh cases what is known as dengue haemorrhagic fever (DHF). There are about 22,000 deaths yearly, mainly among children. Dengue is expensive, costing an average of US$1,394 for each hospitalized patient. At least 10 working days are lost in each case. About 2.5 billion people live in more than 100 endemic countries and area where dengue viruses can be transmit. There is now no cure or vaccine for dengue, although Sanofi Aventis SA has an applicant vaccine in the final stage of clinical development.
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In people who have a high BMI (body mass index), their capillaries are essentially more likely to leak, so that is made worse in a dengue infection," Farrar told Reuters after addressing a communicable disease conference in Singapore. Dengue used to be a disease mainly among young children, but almost anyone is now vulnerable and infection numbers have shot up because of urbanization and the steady movement of people circumstances that allow the Aedes aegypti mosquito, which carries the virus, to thrive.
The World Health Organization estimate there is 50 million dengue infection worldwide each year. Among these are 500,000 harsh cases what is known as dengue haemorrhagic fever (DHF). There are about 22,000 deaths yearly, mainly among children. Dengue is expensive, costing an average of US$1,394 for each hospitalized patient. At least 10 working days are lost in each case. About 2.5 billion people live in more than 100 endemic countries and area where dengue viruses can be transmit. There is now no cure or vaccine for dengue, although Sanofi Aventis SA has an applicant vaccine in the final stage of clinical development.
useful links : transport rankings
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