
A new review of many studies has found some evidence linking heavy alcohol use to accelerated HIV disease progression. In particular, alcohol use influences how dependably people take their medication, which can affect HIV progression. However, it is still unclear whether alcohol affect sequence independently of antiretroviral adherence. “There is strong evidence that alcohol use interferes with antiretroviral therapy adherence. The more a person drinks alcohol, the extra medication he/she misses,” said Professors Judith Hahn and Jeffrey Samet, the authors of the appraisal, in correspondence with The AIDS Beacon.
“Suboptimal obedience to these medications can cause HIV to become opposed to and for the treatment regimen to fail,” they added. However, whether alcohol affects disease progression separately of missed antiretroviral drug doses is more controversial. Scientists have extensive speculated that alcohol and drug use affect the rate of HIV progression. Alcohol is known to have oppressive effects on the immune system, and illegal drug use has been linked to faster progression. However, the role of alcohol in HIV progression has remained elusive. “While many studies conduct in the early 1990s found no link between alcohol use and HIV disease progression, more recent studies have recommended that there is such a link,” said the authors.
To better recognize the connection between alcohol and disease progression, the authors of the review examine a number of studies from before and after the arrival of antiretroviral therapy, as well as animal studies where alcohol use was extra controlled. Results show that prior to the advent of highly active antiretroviral therapy (HAART), studies found no association between heavy alcohol consumption and HIV disease progression. However, more fresh studies from the post-HAART era have been inconclusive. Three of the six studies from the post-HAART era included in the review established an association between heavy alcohol use and at least one measure of HIV disease series, such as higher viral load, lower CD4 count, opportunistic infections, or death.
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“Suboptimal obedience to these medications can cause HIV to become opposed to and for the treatment regimen to fail,” they added. However, whether alcohol affects disease progression separately of missed antiretroviral drug doses is more controversial. Scientists have extensive speculated that alcohol and drug use affect the rate of HIV progression. Alcohol is known to have oppressive effects on the immune system, and illegal drug use has been linked to faster progression. However, the role of alcohol in HIV progression has remained elusive. “While many studies conduct in the early 1990s found no link between alcohol use and HIV disease progression, more recent studies have recommended that there is such a link,” said the authors.
To better recognize the connection between alcohol and disease progression, the authors of the review examine a number of studies from before and after the arrival of antiretroviral therapy, as well as animal studies where alcohol use was extra controlled. Results show that prior to the advent of highly active antiretroviral therapy (HAART), studies found no association between heavy alcohol consumption and HIV disease progression. However, more fresh studies from the post-HAART era have been inconclusive. Three of the six studies from the post-HAART era included in the review established an association between heavy alcohol use and at least one measure of HIV disease series, such as higher viral load, lower CD4 count, opportunistic infections, or death.
useful links : transport rankings
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