Psoriatic Arthritis Suffers Have Vitamin D Insufficiency

A high prevalence of vitamin D insufficiency and deficiency between patients with psoriatic arthritis has been identified in a new research. Seasonal variation in vitamin D levels was not experiential in patients in southern or northern locations. The findings available today in Arthritis Care & Research, a journal of the American College of Rheumatology (ACR), also show no association stuck between disease activity and vitamin D level.

Psoriasis is a general chronic skin disorder, likely cause by an autoimmune response, and is characterized by red scaly patches on the surface of the skin. When accompany by inflammatory arthritis the condition is known as psoriatic arthritis (PsA)-a disease gaining community attention with the recent diagnosis of professional golfer, Phil Mickelson. Studies propose that psoriasis occurs in up to 3% of the world population and approximately one third of these patients have PsA with prevalence estimate ranging from 6% to 42%.

"Vitamin D deficiency is a widespread concern," explains guide study author Dafna Gladman, MD, FRCPC, Director of the University of Toronto Psoriatic Arthritis Clinic in Canada. "And it is more general to see individuals’ living in Northern regions with a deficiency in vitamin D than in persons who reside in Southern areas." Medical evidence show that vitamin D deficiency is more general in individuals living at higher latitudes during the winter, suggesting the deficiency is a result of condensed sun exposure. Furthermore, several studies contain report reduced levels of vitamin D in patients with autoimmune diseases such as rheumatoid arthritis, universal lupus erythematosus, and scleroderma.

Vitamin D helps avoid Alzheimer's diseases

A new study in International Journal of Neuroscience recommends that vitamin D deficiency intensifies the spatial knowledge deficit in Alzheimer's disease, a ordinary form of dementia. The study led by Taghizadeh M. at Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran and colleagues found rats with Alzheimer's disease on a diet without vitamin D did worse in the Morris water maze than their counterparts that inspired a diet supplement with vitamin D. The authors say in their study report that early studies have provide proof that nutrition is associated with neurodegenerative Alzheimer's disease.

Specifically, rats deficient of vitamin D displayed a inferior spatial learning capability compared to their counterparts on the vitamin D supplemented diet. On the other hand, vitamin D supplementation did not considerably affect spatial performance. The researchers wrote "although vitamin D shortage strengthens the spatial learning insufficiency in AD, a supplement of 1,25(OH)2D3 does not efficiently underlie the maze performance. It can be finished that subjects with AD (Alzheimer's disease) must be protected from vitamin D inadequacy." An predictable 5 million Americans live with Alzheimer's disease. There be no cure for the disease.

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